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Publications

Selected Peer-Reviewed Publications

Young JJ, Pedersen JR, King LK, Zywiel M, Perruccio AV, Chandran V, Rampersaud YR, Hawker G, Briggs AM, Hartvigsen J, Koes B. Global research priorities for back pain, neck pain and osteoarthritis: A scoping review. BMJ Open. 2026 Aug. PubMed

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Robb KP, Rabani R, Vohra S, Singh S, Chahal J, Audet J, Perruccio AV, Naraghi A, Gandhi R, Espin-Garcia O, Viswanathan S. Responders vs. non-responders to mesenchymal stromal cells in knee osteoarthritis: Mechanistic correlates of donor cell and patient features. Stem Cell Reports. 2026 Aug. PubMed

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Perry TA, Deng Y, Hulley PA, Maciewicz RA, Mitchelmore J, Larsson S, Gogain J, Brachat S, Struglics A, Appleton CT, Kluzek S, Arden NK, Felson D, Bondi L, Kapoor M, Lohmander LS, Welting TJ, Walsh DA, Valdes AM, Jostins-Dean L, Watt FE, Tom BDM, Vincent TL. STEpUP OA Consortium. Large-scale molecular endotype discovery in synovial fluid reveals osteoarthritis as a single biological continuum. Nat Commun. 2026 Jun. PubMed

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Mesaroli G, Perruccio AV, Davidge KM, Stinson J. Maintaining validity of neuropathic pain screening tools over time: Challenges and opportunities.

J Patient Rep Outcomes. 2026 Jun. PubMed

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Sadeghirad B, Khalili M, Busse JW, Abdelkader W, Foroutan F, Mbuagbaw L, Gilron I, Khan J, Madden K, Tushinski D, Bohm E, Gademan MGJ, Poolman RW, Adili A, Perruccio AV, Rampersaud YR, Righolt C, Shanthanna H, Khaled M, Gabbott B, Marcucci M, Zalzal P, Griffin X, Schemitsch E, Iorio A; McMaster-PROSPER Investigators. Development of risk prediction model for chronic pain after knee replacement surgery: protocol for an individual patient data meta-analysis. Perioper Med (Lond). 2026 Mar. PubMed

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Liu M, Gill R, Gandhi R, Huang J, Furey A, Perruccio A, Rampersaud R, Mahomed NN, Rahman P, Kapoor M, Zhai G. Suggestive Association Between Tryptophan-indole Metabolic Pathway and Total Joint Arthroplasty Early Revision for Heterogeneous Failure Modes in Patients With Primary Osteoarthritis: A Meta-analysis of Metabolomics. J Am Acad Orthop Surg Glob Res Rev. 2026 Mar. PubMed

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Rampersaud YR, Power JD, Nahanni C, Fine N, Canizares M, Kapoor M, Perruccio AV. The impact of overall lumbar disc degeneration burden on disability outcome following surgery for lumbar spinal stenosis due to osteoarthritis. Osteoarth Cartil Open. 2026 Feb. Science Direct

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Mesaroli G, Davis AM, Perruccio AV, Davidge KM, Campbell F, Sun N, Walker SM, Hess CW, Simons LE, Logan D, Stinson JN. Item Reduction and Scoring of the Pediatric PainSCAN©: A Screening Tool for Pediatric Neuropathic Pain and CRPS. Clin J Pain. 2025 Nov. PubMed

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Perruccio AV, Kral C, Yip C, Eder L, Power JD, Canizares M, Wilfong JM, Heckman G, Badley E. The role of sex and systemic inflammation in the development of cardiovascular disease in osteoarthritis: A population-based cohort study using the CLSA. Semin Arthritis Rheum. 2025 Oct. PubMed

 

Perruccio AV, Power JD, Sundararajan K, Canizares M, Davey JR, Gandhi R, Syed K, Veillette C, Kapoor M, Mahomed NN, Rampersaud YR. Sex Matters: Investigating the Influence of Presurgery Factors on Pain and Physical Function following Total Joint Arthroplasty for Osteoarthritis. JB JS Open Access. 2025 Nov. PubMed​

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Mesaroli G, Davis AM, Perruccio AV, Davidge KM, Campbell F, Sun N, Walker SM, Hess CW, Simons LE, Logan D, Stinson JN. Reliability and validity of the Pediatric PainSCAN: A screening tool for pediatric neuropathic pain and complex regional pain syndrome. Pain. 2025 Jul. PubMed

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Cavallo M, Badley EM, Perruccio AV. Insomnia symptoms among individuals with osteoarthritis and symptoms indicative of osteoarthritis: A population-based cross-sectional study using the CLSA. PLoS One. 2025 May. PubMed

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Young JJ, Zywiel MG, Skou ST, Chandran V, Davey JR, Gandhi R, Mahomed NN, Syed K, Veillette CJH, Rampersaud YR, Perruccio AV. Total Hip Arthroplasty versus Education and Exercise: A Secondary Analysis of Propensity Matched Data Comparing Outcomes Across Hip Osteoarthritis Symptom Severity. J Arthroplasty. 2025 May. PubMed

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Rockel JS, Sharma D, Espin-Garcia O, Hueniken K, Sandhu A, Pastrello C, Sundararajan K, Potla P, Fine N, Lively SS, Perry K, Mahomed NN, Syed K, Jurisica I, Perruccio AV, Rampersaud YR, Gandhi R, Kapoor M. Deep learning-based clustering for endotyping and post-arthroplasty response classification using knee osteoarthritis multiomic data. Ann Rheum Dis. 2025 Feb. PubMed

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Deng Y, Perry TA, Hulley P, Maciewicz RA, Mitchelmore J, Perry D, Larsson S, Brachat S, Struglics A, Appleton CT, Kluzek S, Arden NK, Felson D, Marsden B, Tom BDM, Bondi L, Kapoor M, Batchelor V, Mackay-Alderson J, Kumar V, Lohmander LS, Welting TJ, Walsh DA, Valdes AM; STEpUP OA Consortium; Vincent TL, Watt FE, Jostins-Dean L. Development of methodology to support molecular endotype discovery from synovial fluid of individuals with knee osteoarthritis: The STEpUP OA consortium. PLoS One. 2024 Nov. PubMed

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Peters H, Potla P, Rockel JS, Tockovska T, Pastrello C, Jurisica I, Delos Santos K, Vohra S, Fine N, Lively S, Perry K, Looby N, Li SH, Chandran V, Hueniken K, Kaur P, Perruccio AV, Mahomed NN, Rampersaud R, Syed K, Gracey E, Krawetz R, Buechler MB, Gandhi R, Kapoor M. Cell and transcriptomic diversity of infrapatellar fat pad during knee osteoarthritis. Ann Rheum Dis. 2024 Oct. PubMed

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King LK, Young JJ, Grønne DT, Bricca A, Roos EM, Skou ST, Hawker GA. GLA:D to Be Walking Better: Change in Self-Reported Difficulty Walking After Exercise Therapy and Education in Persons With Knee Osteoarthritis. J Rheumatol. 2024 Oct. PubMed

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Harsted S, Chang NHS, Nim C, Young JJ, McNaughton DT, O'Neill S. Exploring the association between patient-drawn pain diagrams and psychological and physical health variables: A large-scale study of patients with low back pain. Eur J Pain. 2024 Aug. PubMed

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Badley EM, Zahid S, Wilfong JM, Perruccio AV. Labour Force Participation in Adults with Osteoarthritis (OA) or Joint Symptoms Typical of OA: Findings from a Canadian Longitudinal Study on Aging. Arthritis Care Res (Hoboken). 2024 Jul. PubMed

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Wilfong JM, Badley EM, Perruccio AV. Old before their time? The impact of osteoarthritis on younger adults. Arthritis Care Res (Hoboken). 2024 May. PubMed

 

Power JD, Perruccio AV, Canizares M, Davey JR, Gandhi R, Mahomed NN, Syed K, Veillette C, Rampersaud YR. The impact of diabetes status on pain and physical function following total joint arthroplasty for hip and knee osteoarthritis: variation by sex and body mass index. Sci Rep. 2024 May. PubMed

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Chang NHS, Nim C, Harsted S, Young JJ, O'Neill S. Data-driven identification of distinct pain drawing patterns and their association with clinical and psychological factors: a study of 21,123 patients with spinal pain. Pain. 2024 May. PubMed

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Young JJ, Zywiel MG, Skou ST, Chandran V, Davey JR, Gandhi R, Mahomed NN, Syed K, Veillette CJH, Rampersaud YR, Perruccio AV. Total Hip Arthroplasty Versus Education and Exercise: A Propensity-Matched Analysis of 266 Patients Who Have Hip Osteoarthritis. J Arthroplasty. 2024 Apr. PubMed

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Power JD, Trifoi F, Canizares M, Perruccio AV, Shanmugaraj A, Gandhi R, Davey JR, Syed K, Mahomed NN, Veillette C, Rampersaud YR. The impact of diabetes on physical and mental health status and patient satisfaction after total hip and knee arthroplasty. Plos One. 2024 Apr. PubMed

 

Mesaroli G, Davidge K, Davis A, Perruccio AV, Choy S, Walker S, Stinson J. Age and sex differences in pediatric neuropathic pain and complex regional pain syndrome: A scoping review. Clinical Journal of Pain. 2024 Apr.

PubMed

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Perruccio AV, Yip C, Power JD, Canizares M, Badley EM. Examining the longitudinal associations between activity limitations, instrumental supports and social participation in osteoarthritis: A CLSA population-based study. PLoS One. 2024 Mar. PubMed

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Young JJ, Zywiel MG, Skou ST, Chandran V, Davey JR, Gandhi R, Mahomed NN, Syed K, Veillette CJH, Rampersaud YR, Perruccio AV. Total knee arthroplasty versus education and exercise for knee osteoarthritis: a propensity-matched analysis. Arthritis Care Res (Hoboken). 2024 Jan. PubMed

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Canizares M, Power JD, Perruccio AV, Paterson M, Mahomed NN, Rampersaud YR. High health care use prior to elective surgery for osteoarthritis is associated with poor postoperative outcomes: A Canadian population-based cohort study. J Health Serv Res Policy. 2023 Dec. PubMed

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Perruccio AV, Young JJ, Wilfong JM, Denise Power J, Canizares M, Badley EM. Osteoarthritis Year in Review 2023: Epidemiology & therapy. Osteoarthritis Cartilage. 2023 Nov. PubMed

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Canizares M, Power JD, Perruccio AV, Veillette C, Mahomed N, Rampersaud YR. Time trends and patterns in opioid prescription use following orthopaedic surgery in Ontario, Canada, from 2004/2005 to 2017/2018: a population-based study. BMJ Open. 2023 Nov. PubMed

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Young JJ, Kongsted A, Hartvigsen J, Ammendolia C, Jensen RK. Similar improvements in patient-reported outcomes for non-specific low back pain patients with and without lumbar spinal stenosis symptoms following a structured education and exercise therapy program. BMC Musculoskelet Disord. 2023 Oct. PubMed

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Perruccio AV, Badley EM, Antflek D, Power JD, Baltzer H. Frequency of multisite non-hand joint involvement in patients with thumb-base osteoarthritis, and associations with functional and patient-reported outcomes. Osteoarthr Cartil Open. 2023 Aug. PubMed

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Young JJ, Perruccio AV, Veillette CJ, McGlasson RA, Zywiel MG. The GLA: D® Canada program for knee and hip osteoarthritis: A comprehensive profile of program participants from 2017 to 2022. Plos one. 2023 Aug. PubMed​

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Wilfong JM, Perruccio AV, Badley EM. Examination of the Increased Risk for Falls Among Individuals With Knee Osteoarthritis: A Canadian Longitudinal Study on Aging Population-Based Study. Arthritis Care Res (Hoboken). 2023 May. PubMed

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Young JJ, Kongsted A, Jensen RK, Roos EM, Ammendolia C, Skou ST, Grønne DT, Hartvigsen J. Characteristics associated with comorbid lumbar spinal stenosis symptoms in people with knee or hip osteoarthritis: an analysis of 9,136 good life with osteoArthritis in Denmark (GLA:D®) participants. BMC Musculoskelet Disord. 2023 Apr. PubMed

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Perruccio AV, Zahid S, Yip C, Power JD, Canizares M, Heckman GA, Badley EM. Cardiovascular Risk Profile and Osteoarthritis-Considering Sex and Multisite Joint Involvement: A Canadian Longitudinal Study on Aging. Arthritis Care Res (Hoboken). 2023 Mar. PubMed​

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Schneider CH, Parambath S, Young JJ, Jain S, Slater H, Sharma S, Kopansky-Giles D, March L, Briggs AM. From Local Action to Global Policy: A Comparative Policy Content Analysis of National Policies to Address Musculoskeletal Health to Inform Global Policy Development. Int J Health Policy Manag. 2023 Jan. PubMed

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Briggs AM, Betteridge N, Dreinhöfer KE, Haq SA, Huckel Schneider C, Kalla AA, Kopansky-Giles D, March L, Sharma S, Soriano ER, Woolf AD, Young JJ, Slater H. Towards healthy populations: A need to strengthen systems for musculoskeletal health. Semin Arthritis Rheum. 2022 Dec. PubMed​

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Badley EM, Wilfong JM, Chan CH, Canizares M, Perruccio AV. I don't know what type of arthritis I have: A population-based comparison of people with arthritis who knew their specific type and those who didn't. PLoS One. 2022 Jun. PubMed

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Power JD, Perruccio AV, Paterson JM, Canizares M, Veillette C, Coyte PC, Badley EM, Mahomed NN, Rampersaud YR. Healthcare Utilization and Costs for Musculoskeletal Disorders in Ontario, Canada. J Rheumatol. 2022 May. PubMed​​

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Perruccio AV, Wong JTY, Badley EM, Power JD, Yip C, Rampersaud YR. Predictors of response following standardized education and self-management recommendations for low back pain stratified by dominant pain location. N Am Spine Soc J. 2021 Nov. PubMed​

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Badley EM, Zahid S, Wilfong JM, Perruccio AV. Relationship Between Body Mass Index and Osteoarthritis for Single and Multisite Osteoarthritis of the Hand, Hip, or Knee: Findings From a Canadian Longitudinal Study on Aging. Arthritis Care Res (Hoboken). 2021 Jun. PubMed

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Perruccio AV, Power JD, Yip C, Badley EM, Canizares M, Rampersaud YR. The impact of multijoint symptoms on patient-reported disability following surgery for lumbar spine osteoarthritis. Spine J. 2020 Aug. PubMed​​

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Wilfong JM, Badley EM, Power JD, Gandhi R, Rampersaud YR, Perruccio AV. Discordance between self-reported and performance-based function among knee osteoarthritis surgical patients: Variations by sex and obesity. PLoS One. 2020 Jul. PubMed​

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Perruccio AV, Yip C, Power JD, Canizares M, Gignac MAM, Badley EM. Understanding the Association Between Osteoarthritis and Social Participation: The Canadian Longitudinal Study on Aging. Arthritis Care Res (Hoboken). 2020 Jun. PubMed

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Wilfong JM, Perruccio AV, Millstone DB, Badley EM. Participation in Informal Caregiving Among People With Arthritis: Findings From a Canadian Longitudinal Study on Aging. Arthritis Care Res (Hoboken). 2020 May. PubMed

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Badley EM, Wilfong JM, Yip C, Millstone DB, Perruccio AV. The contribution of age and obesity to the number of painful joint sites in individuals reporting osteoarthritis: a population-based study. Rheumatology (Oxford). 2020 Apr. PubMed

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Yip C, Badley EM, Canizares M, Power JD, Perruccio AV. Risk Factor Profiles for Individuals With Diagnosed OA and With Symptoms Indicative of OA: Findings From the Canadian Longitudinal Study on Aging. ACR Open Rheumatol. 2020 Mar. PubMed​

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Rampersaud YR, Power JD, Perruccio AV, Paterson JM, Veillette C, Coyte PC, Badley EM, Mahomed NN. Healthcare utilization and costs for spinal conditions in Ontario, Canada - opportunities for funding high-value care: a retrospective cohort study. Spine J. 2020 Jan. PubMed

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Badley EM, Goulart CM, Millstone DB, Perruccio AV. An Update on Arthritis in Canada - National and Provincial Data Regarding the Past, Present, and Future. J Rheumatol. 2019 Jun. PubMed​​

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For a full list of Dr. Elizabeth Badley's publications, please follow this link.

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For a full list of Dr. Anthony Perruccio's publications, please follow this link.

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Contact Us

Schroeder Arthritis Institute

University Health Network

399 Bathurst Street
Toronto, Ontario   M5T 2S8

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Email: acreu@uhn.ca

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